Multifunctinal Electro Fusion & Electroporation Unit with Hybridoma Production
Make
BTX Harvard Apparatus
Model
ECM-2001 LITE
Multifunctional electro fusion and electroporation unit with hybridoma production is a laboratory instrument used for the production of monoclonal antibodies. The instrument is capable of performing electroporation and electrofusion, two techniques commonly used in the production of hybridomas, which are immortal cell lines created by fusing a B cell with a myeloma cell.
Electroporation is a technique used to introduce nucleic acids or other molecules into cells by applying a high voltage electric field. The electric field causes pores to form in the cell membrane, allowing molecules to enter the cell. Electroporation is commonly used to introduce plasmids or other DNA into cells for genetic engineering purposes.
Electrofusion is a technique used to fuse two cells together by applying a high voltage electric field. In hybridoma production, electrofusion is used to fuse a B cell, which produces the desired antibody, with a myeloma cell, which provides immortality to the resulting hybridoma cell line.
Overall, the multifunctional electro fusion and electroporation unit with hybridoma production is a versatile laboratory instrument that combines the power of electroporation and electrofusion to enable the efficient production of hybridomas and other applications requiring the introduction of molecules into cells.